dirty genes, epigenetics, maladaptive Western diets & lifestyles, environmental factors play into our chronic illness problem
So the presumption was that you really just need your basic macronutrients – carbohydrates, proteins, fats, etc., and the mitochondria will take care of everything. What is ignored is that to get from those macronutrients to ATP you actually need functional enzymes and you need micronutrients – vitamins and minerals at each step and there’s 22 of them you need. Thiamine happens to be the most important because of its geographic position, if you will, and because of its great limiting step along the various pathways.
No matter what other deficiency you may or may not have, if you do not address thiamine you will never heal. It’s not the only vitamin you need, but it’s the one you absolutely must address before you deal with everything else. I think that’s the most difficult thing for people to realize and why folks will go on these things with folate and B12 and this, that and the other thing, forgetting entirely that that’s so much further down the pathway than thiamine. So they wonder why they don’t heal and they seem to think, “Well it must not be the nutrients. It’s not the vitamins. I’ve done the vitamin thing and it’s not working.” But they haven’t done the right ones yet.
— Chandler Marrs, PhD. and editor of Hormones Matter April 2019 interview
In so many deceptive and not so deceptive ways, Western Medicine has failed a great many hundreds of millions of people. Anything tagged “Western” under this penury and punitive parasitic-reactionary-zombie-shock-to-the-system capitalism is more than just suspect when one looks at the project of finance and command and control the financiers of the world have unleashed for several hundred years.
Western Agriculture (the so-called greening of farming with former Nazi chemists retrofitting war tools into farmers’ nerve agents, hormone disrupters, brain scrambling toxins into the war against nature, i.e., the so-called green revolution) we can ask, how is that working out for humankind? It doesn’t take a Michael Pollan to understand that just the Western diet and the loads of preservatives, emulsifiers, anti-caking tricks, nanoparticles and fake, cheap, trickster ingredients — thanks to Western Life Goes Better with Chemicals paradigm – are killing Americans and others tied to these crack cocaine delivery systems supplying the West with “nutritional” and “farming” beasts of a nation. .
We can’t mix apples and oranges, can we, as we are told by Western Mass Media, et al, when we couple the war on human food with the war on ecology and nature, which is what agriculture has unleashed and continues to supercharge this highly industrialized, mono-culture focused, scaled-up version of a Brave New Farm New Order consumer pipeline. Water polluted, aquifers drained, rivers clogged, dams the old-new normal, most wild systems destroyed, fractured and quickly endangered, and, well you have a system that is sick under any person’s definition of the word or concept of “illness.”
However, hand in hand goes the medical and pharma communities lavishly gaining trillions in profits from this pipeline of cancer-causing, heart-disease tripping, stroke-inducing, diabetes-setting high fat-salt-sugar-meat-dairy diet. In part, the medical community has facilitated reinforcing that death pipeline through co-option of the “normalcy” of capital and profits ruling the market — ruling citizens by flipping us into consumers, perennial patients, targets, marks, victims, Guinea pigs, and then chucking any sense of the precautionary principle in lieu of our so called better angels (actual devils of GMOs, HFCS, hyphenated carcinogens).
Every doctor making a cool five million bucks a year on gastric by-passes, heart surgeries, diabetes maintenance programs and cancer-treatments is part of the problem.
Doctors invest in Pizza Hut, Coca Cola, Merck, Monsanto, and whatever bulks up their investment portfolios. Their well-being and their families’ well-being and their rich status in our New Gilded Age society are dependent/interdependent on disease treatment, disease maintenance, disease-embracing medicine, and disease as the new normal.
What goes into Johnny’s gullet-lungs-brain comes back to the rich and Western elite in literal gold reserves and hedge fund derivatives.
So, Western Industrialization – in agriculture, in medicine, in food, in education, in production lines – greased vis-à-vis those economy of scales that aid and abet putting out of business any sane (AKA alternative) treatment modality (naturopathic, holistic, Eastern “medicine” steeped in health care preventative models), or holistic food system (agroecological, organic, scaled to human size farming), or education program (the whole person, intergenerational, creative, hands on, sans core curriculum and standardized test model kind) –is not just the bane of humanity, big or small communities, but also the bane of civilization as we know it.
Any veterinarian looking at an over-sized, arthritis-prone, pre-diabetic, sluggish, tired, itchy skin, anxious, stinky mouthed youngish Labrador Retriever will prescribe more veggies, no commercial dog food (of the rendered roadkill variety) lean chicken, rice, carrots, corn, squash, err, a vegetarian diet.
The human patient doctors really are glad the advertisement says, “Things deep-fried, refined, greasy, meat-centric do go better with Coca Cola.” Money, money, money, guaranteed job security, great gobs of power in our society as sickness and disease come to younger and younger cohorts with each passing year.
Johnny, Juanita, Quyen, Ahmed are Dining on Death
It goes without saying that anyone following my polemics and non-polemical writing know that I am solidly anti-corporation, anti-top down government, and for peace colleges, for an entirely new and different educational system, and that’s not just for PK12, but lifelong education. I am for scaling down, localizing, and working bio-regionally and globally on these systems of pain, oppression, subjugation, and disease.
We are only going to get out of this plundering, and end these enslaved systems of oppression, pollution, and lobotomy through ecosocialism and a true people’s contract through a people’s direct democracy, and strong collective engagement and education.
The revolution will not happen here in the USA, as we know, and when I say revolution, I am speaking about all of those systems of penury and oppression tied to the Military-Prison-Chemical-Pharmacological-Fossil Fuel-Finance-Banking-Insurance-Medical-IT-Real Estate-Education-Legal-AI Complex going down down gone!
While I parachute into jobs tied to the social services, homeless citizen services, PK12 education, environmental activism, localized community rights building, art, literature, politics, media, journalism, anti-poverty programs, I get more than a bird’s eye view of the systems of oppression in this white supremacist patriarchal society.
Just three days ago, I was the teacher of record (substitute) with seven para-educators (women who not only assist that special ed classroom, but who are also teachers, aides, psychologists, so to speak) as I worked an elementary school’s special education self-contained classroom.
First, the parents of these children are amazing, but they are hobbled not only by poverty, by their working class struggle, and by the vagaries of paying so much to live in poverty, but also by these special needs children.
These children are mostly honored and loved.
Then those seven hours, five days a week, in a school, these youth are then shepherded by caring people working under systems of oppression and penury and disappearing funding, until alas, these educational frameworks become failures.
And to what end? Young kids I taught Monday were 6, 7, 8, 9, 10 years old. Where will they be when they hit 18 or 21? The society is not planning for their adulthood, for their needs, for their pathway to some sense of independence. Think living on the streets or staying at home until parents die.
This is the problem, now, is it not? Youth who need one-on-one, sometimes two staff-to-one child attention. The funding isn’t there, and when localities face budget constraints, they go after the “lower rung,” to include firing/laying off para-educators. No teacher in her right mind would have a classroom of a dozen or more youth with behavioral, developmental, intellectual disabilities under her wing WITHOUT the support of paraeducators.
A million people have a million “ideas” and “opinions” about what is wrong and needs fixing with education, but in the end, the American hating, trolling, everyone’s opinion is sacrosanct citizen is more than out to lunch when it comes to almost every armchair prognostication made.
We put young and old immigrants in cages, or these wire boxes where most anyone in this society would not dare put their pet dogs in, and yet we let children die, force children away from family, and, well, a society that accepts that (and by it happening, we all accept that sort of Gestapo Nazi style of punishment), will easily accept the broken and breaking systems of education we have come to see in thousands of communities across the land.
Is it any wonder that the food we feed these special education students is one hot mess of triple fat, triple salt, triple carbs, triple sugar?
Children – either deemed special ed or behaviorally challenged, or gifted and talented – are being fed the most perverse diets on earth. Flooded with empty calories and dead-end oils that are toxic and inflammatory, but also chemicals that make up the ingredient list on a box of crackers that hardly any college educated person can pronounce, let alone understand the origins and consequences on the human physiology, the food (sic) served is deadly. Daily deadly dose of cafeteria (they don’t cook in school cafeterias anymore, but microwave prepacked junk) slop.
Pollution Starts with the Polluting of the Mind
Polluting people with propaganda, with bad food, bad air, bad soil, bad water, bad culture, and, alas, these children in special education are dealing with a multitude of issues they will never fully or even partially get out from under.
Chronic disease, chronic fatigue, chronic brain fog, chronic pain, chronic anxiety, chronic addiction, chronic confusion, chronic anger, chronic discombobulation, all of it have their origins right smack in the center of the gooey nougat of death-inducing capitalism.
I’m interested in people thinking outside of the box, and pushing against the paradigms of oppression, in any arena, whether it’s industry, big oil, big finance, or, in this article’s case, medicine.
How many times does a guy who is pugnacious and pugilistic get to interview a doctor whose pedigree goes way back – he’s alive and well, age 95, living in England?
Old school – mandatory (national service) in the RAF (7 years) in England, and working for the national health service in the UK (10 years).
I have been tracking the work of people like Derrick Lonsdale around naturopathy, the foods-vitamins-lifestyles-vaccinations connection for decades. I have looked at the value of Vitamin and Herbal Supplemental enrichment in our lives for years — lifestyles broken by the chemical exposures, the pesticides exposures, the drug exposures, the pollution exposures, the GMO exposures, the electrical magnetic frequency (WiFi, cellular phone, etc) exposures, the heavy metal exposures.
Add to that the magical thinking, the lobotomizing education systems, the consumer-droning mass media mush, and we have some really hard times in Western Society that is so hobbled by fear, falling in line (in a goosestep sometimes) with the corporate-government narrative, etc.
Autoimmune Disease Goes to the Mitochondria
There are so many maladies tied to autoimmune diseases, bowel conditions, blood issues, and complete endocrine and hormone discombobulation.
In many cases, women especially are deemed hysterical, psychologically-motivated, insane when they come to Western Medicine with such issues listed above –
- Rheumatoid arthritis
- Systemic lupus erythematosus (lupus)
- Inflammatory bowel disease (IBD)
- Multiple sclerosis (MS)
- Type 1 diabetes mellitus
- Chronic inflammatory demyelinating polyneuropathy
- Graves’ disease
- Hashimoto’s thyroiditis
- Myasthenia gravis
I’ve been lucky to have written for Hormones Matter – tied to my mistreatment by social services non-profits and Planned Parenthood for a simple sex ed training class in Seattle where I dared to ask the facilitators with PP that the Gardasil debate was not yet settled.
Here I was as a foster youth social worker, and you can imagine the foster parents that have children in their charge – many are tied to homeschooling and are skeptical of vaccinations. You just need to go to Hormones Matter or just do the Google (if Google hasn’t scrubbed all the evidence against Gardasil) and put in “ Merck and Gardasil and criticism and lawsuits.” What have you.
Derrick along with Hormones Matter editor, Chandler Marrs, have written an amazing book, Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition.
Go to Hormonesmatter (dot) com and check out the depth of the articles, depth of the outside the Western Medicine Paradigm the articles address. Writers who are PhD’s, MDs, or experts through their own trials and tribulations suffering under myriad of diseases.
Here’s my interview:
- So you are 95 years old, and have seen many changes in Western Society and innovative arenas of thought and knowledge around disease and human health. What are some of the biggest impacts you believe from your learning have greatly changed the way you see health?
DL — What are some of the most troubling aspects of medicine and health you can discuss after, what, more than 50 years in medicine?
I started my medical career, after National Service as a medical officer in the RAF, in family practice for 7 years under the NHS. Not liking the bureaucracy I immigrated to Canada with a short service commission in the RCAF. I did residency in pediatrics at Cleveland Clinic and in 1962 I was invited to join the staff.
I was on the pediatric staff at the Cleveland Clinic from 1962 to 1982. I headed a section on biochemical genetics. A six year old boy who had repeated episodes of brain disease had every conventional test normal. He proved to be the first case of vitamin B1 dependency, a mutation in the gene that enabled glucose to fuel energy metabolism. It changed my professional life. With the extensive library research required, I learned the details of energy metabolism and began to be aware that it was the core issue of disease. I began to realize that the present medical model, dependent on the Flexner report of 1910, is inadequate. I found that so many of the children referred to the Clinic were emotionally sick from diet rather than from poor parenting. I published a suggested new medical model, based on a combination of genetics/environmental stress/and energy, represented as three interlocking circles. The body is an electrochemical “machine” and if the genetic code is perfect (it never is) all it requires is energy.
Genetic mutations seldom act by themselves. Another factor comes into play, giving rise to the gene expression. Diabetes sometimes makes its first appearance after a cold or an injury, strongly indicating that energy deficiency affects the gene(s) at root. The troublesome aspects of modern medicine are far reaching. The profession has been taken over by the insurance companies and the pharmaceutical industry. Drugs only treat symptoms and do not address cause. Surgery to remove a sick organ is tacitly an admission of medical failure.
2. Great scientists like Robert Sapolsky have looked at the diseases of Homo sapiens as they are tied to stress, as in his book, Why Zebras Don’t Get Ulcers
DL — Hans Selye was the great interpreter of the physiologic and pathophysiogic effects of stress. He was able to show that the General Adaptation Syndrome (GAS) in experimental animals required energy for the animal to adapt to the many forms of stress that he used in his experiments. Lab data obtained from stressed animals imitated the lab data from sick humans and he formulated the idea that human diseases were “the diseases of adaptation”. One of his students was able to produce the GAS by making the animal thiamine deficient, thus showing the importance of energy metabolism. The only way that we can help the body in synthesizing the required energy is by providing the right fuel and the catalysts that enable oxidation to occur efficiently. Pharmaceuticals only address symptoms but do nothing for their underlying cause.
3. Discuss your work and knowledge around just the real and perceived stress of our Western Culture (not tied to our Western diets . . . that’s for a later question) and how that plays havoc on the human biological system?
DL– Well, I guess that comes under the heading of stress. Just like Selye’s animals, we require energy to adapt b. . . meaning that our brain/body complex defense mechanisms go into action. We live in a world that takes little notice of our biology. The further we get away from it the greater the risk. There are thousands of toxic chemicals that increase the stress load. The relatively new science of epigenetics has yet to emerge in clinical medicine. This, as you know, is the science of how nutrition and lifestyle influence our genes. Epigenetics is even emerging in the complex field of cancer.
4. On Hormones Matter, you have many articles tied to thiamine deficiency, but also other areas –
October 14, 2019, Sleep Requires Energy
September 30, 2019, A New Medical Model to Prevent Physician Burnout
September 17, 2019, SIDS and Vaccination
September 12, 2019, Juvenile Rheumatoid Arthritis: An Unusual Treatment
August 22, 2019, When Glaucoma Is More Than an Eye Disease
July 1, 2019, Energy Loss as a Cause of Disease
DL — Yes, but they are all tied to our capacity to synthesize energy. I did sabbatical in Australia after David Read published thiamine deficiency as a cause of SIDS. My colleagues and I published abnormal auditory brain-stem evoked potentials in threatened SIDS and showed that megadose thiamine stopped the apnea alarms from ringing. We also published our work. Thiamine deficiency disease gives us the prototype for dysautonomia. Interestingly, many case reports of dysautonomia have been published in association with an assortment of diseases, without recognizing the importance of the association. I have suggested that it hallmarks the association as evidence that each disease is caused by oxidative inefficiency. The dysautonomia is really very much part of the disease expression.
5. So, Dr. Lonsdale, there seems a sense of urgency in these pieces, and the thread to each of them goes to deficiency in nutrition. Why is it in 2019, we have Western medicine treated disease rather than preventing disease?
DL — A good question. The medical profession as a whole has rejected the deficiency of non caloric nutrients as a common cause of disease. They claim that vitamin enrichment has abolished them and that these diseases are only of historical interest. Hence they are not familiar with the symptoms that would have been recognized 70-80 years ago. Many of these patients are diagnosed as “psychosomatic” and there are probably millions of Americans affected. Any physician who claims that a patient’s symptoms are due to (e.g.)beriberi is considered to be “off his head” and is exactly what happened to me at Cleveland Clinic. I actually saw beriberi in CCH patients and nobody would believe me. I have outlined their cases in our book that needs to be read by every physician, since laboratory proof is used.
6. We have in the USA more than 150 million people with at least chronic illness, many with co-occurring. We have an obesity epidemic? We have a society that is fed the propaganda of Madison Avenue. How do you see this logjam getting broken when so much of Western Medicine “depends” on the food industries of high salt, far, sugar?
DL — Chandler [Marrs] and I are more than convinced that thiamine deficiency is widespread because this deficiency is easily induced by inordinate ingestion of sugar in many different forms. The last statistics that I saw for the U.S. was 150 pounds of sugar per capitum per annum. We have suggested that the early symptoms, if recognized at onset, are easily treated. We believe that if there is failure to recognize them, chronic disease follows later, giving rise to an assortment of neurodegenerative diseases. Each is named by the first individual to recognize the repeated appearance of a constellation of symptoms and signs (Parkinson, Alzheimer etc). Not acknowledging the overlap of these symptoms in patients with a diagnosis of one disease versus another, each is thought to have a separate cause that must be specifically identified as a “cure”. We regard that as trying to shut the stable door after the horse has gone.
In 1936 Sir Rudolph Peters opened the studies of oxidative metabolism by the discovery of the catatorulin effect. He showed that there was no difference in the respiration of thiamine deficient pigeon brain cells compared with cells from a thiamine replete pigeon until glucose was added to the preparation. The thiamine sufficient cells immediately began to respire, whereas the TD cells did not. I have seen hundreds of patients whose extremely variable symptoms were due to mild to moderate thiamine deficiency and proved it via lab testing.
7. Where do you see the work you and Chandler going? Most people I see and work with as a teacher and social worker just can’t understand the axiom – You are what you eat? I could take that further, of course, by saying “you are what you read, do, say, believe, hold dear, don’t believe, hope for, dream of, observe, watch, hear, listen to.”
DL — We believe that we must try to address both physicians and patients, hence our reports on Hormones Matter. It has led to a great deal of correspondence between patients and us. What appalls us is the many years of suffering expressed by many of them and their rejection by their physicians as “problem patients”. One young woman discovered from reading our book that her Flagyl toxicity symptoms were due to TD. Not only did her physician insist that her symptoms were “psychological”, she was rejected from that multi-doctor clinic “ because she would not accept the psychology diagnosis”. Her physician denied Flagyl toxicity even though the symptoms are published.
8. Is it a matter of hormones in most cases you have experienced in both medicine and in communicating with individuals with major physical health concerns?
DL — Hormones enter the picture because they are under the control of the limbic brain with the autonomic system. Energy deficiency in the brain affects their synthesis and their distribution.
9. What could med schools be doing to really help the health of a community, the country?
DL — Med schools have produced research to show that a lot of disease in America is biochemical in origin. Even if these common symptoms are correctly found to be biochemical in origin, they then assume that a drug must be found to correct them. The whole climate of medicine is based on pharmaceutical “genius”.
10. Talk about the violence-hormone-vitamin deficiency connection in more depth, if you will?
Our emotional sensations arise from the lower brain and are tied to the perceived event. They can be modified by the cortex but it implies brain communication. TD is equivalent to a mild degree of hypoxia and is thought of as causing pseudohypoxia. Because this is dangerous to the organism, either of them will excite the tendency to initiate the fight-or-flight reflex behavior. Hence, I see a boy who has had a mild redress in school, nursing it with a sense of human injustice, bursting into nonsensical violence. Nobody has ever questioned a perpetrator as to the quality of his diet. Nobody has reported a physical exam that might show the imprint of dysautonomia. Some years ago a probation officer in Cuyahoga Falls managed to get a judge to bind over juvenile criminals to her for dietary supervision. The recidivity rate fell to virtually zero.
11. What do you attribute your longevity to?
DL — I don‘t know. I do take a lot of supplements
12a. What role does epigenetics play in your research around energy and Vitamin B?
DL — I think that my use of megadoses of thiamine is epigenetic
12b. Diseases of Adaptation v. diseases of maladaptation is what you allude to when speaking of Seyle. Give a connotation and denotation of what this is saying for the average reader to understand.
Stress is defined as a mental or physical environmental force acting on an organism, including humans. Like Selye’s experimental animals such a person first must perceive the form of the stress and adapt to it. Infection excites a defensive response that is organized automatically by the brain. A deadline, a business problem, a divorce etc requires a thought process conducted by the brain. Both physical and mental stress require energy expenditure. It explains why a divorce might result in sickness in one person and not in another, depending on the energy status. In other words the ability to meet life stresses depends on the combination of adequate nutrition and genetics.
13. Industrial agriculture and industrial food and industrial everything have come from the industrial revolution, from then to now. What can we do to reverse this turbo charged world of turbo charged living, eating, consuming and surviving? Your message is clear, smart and elegant, but in Capitalism, we always want to blame the victim, the patient, the person. It’s our fault if we are in constant fatigue, or if we are fat and can’t lose weight, or if we have difficulty dealing with the everyday “norms” of modern society.
DL — I don’t think that we can do anything about altering the cause. All we can do is to repeat and repeat what IS the cause, pointing out HOW it affects us. If a person will not change diet, he/she may well accept supplements because they are trained to taking pills for health correction. Perhaps, artificial as that may be, clinical improvement will enhance the perceived importance of nutrition and lifestyle, acting as a learning process.
14. Where is the new frontier in medicine, in your estimation?
DL — I think that it is in the hands of ACAM [ACAM is the pioneer integrative organization and advocate of education for dedicated professionals who set out to make a difference in the standards of healthcare. Our membership includes MD, DO, ND, ARNP, NP, DC, DDS, scientists, medical students/residents, dietitians, nutritionists, researchers, and more.] and ICIM [The International College of Integrative Medicine is a community of dedicated physicians who advance innovative therapies in integrative medicine by conducting educational conferences, supporting research, and cooperating with other scientific organizations, while always promoting the highest standards of practice.]
15. I have friends and others researching the chemical-human disease connection, to include Dr. Rosemary Mason, looking at the unbelievable amounts of chemicals – poisons – in our ecosystems, food systems, and bodies.
Campaigner and environmentalist Dr Rosemary Mason has written an open letter to the Chief Medical Officer of England, Sally Davies. In it, Mason states that none of the more than 400 pesticides that have been authorised in the UK have been tested for long-term actions on the brain: in the foetus, in children or in adults.
The UK Department of Health (DoH) has previously stated that pesticides are not its concern. But, according to Mason, they should be. She says that Theo Colborn’s crucial research in the early 1990s showed that endocrine disrupters (EDCs) were changing humans and the environment, but this research was ignored by officials. Glyphosate, the most widespread herbicide in the world, is an EDC and a nervous system disrupting chemical.
Speak to these concerns, too, Dr. Lonsdale.
DL — I totally agree but this kind of common sense usually falls on deaf ears. I have entered my posts on the metronidazole toxicity group and sent a letter to the FDA in regard to the nature of its toxicity. It hasn’t changed a thing but a lot of people have been helped. A paper I wrote in 1980 reporting 20 adolescents who had proved thiamine deficiency disease caused my phone to light up but it has long been forgotten. We can only just keep plugging on!!!